Harnessing Agility and Innovation to Unleash the Potential of Discovery Chemistry at Aragen Life Sciences
At Aragen, we are a Contract Research, Development, and Manufacturing Organization (CRDMO) with over 25 years of expertise in providing innovative chemistry solutions. We combine frontier areas of chemistry with cutting-edge digital and AI technologies to accelerate drug discovery and development. Our team of over 2,500+ scientists and 300+ PhDs work in the state-of-the-art laboratories, solving complex synthetic challenges and identifying the most promising molecules for preclinical candidate nomination and development studies that can translate into the clinic.
Advanced technology platforms: Parallel synthesis, direct to biology (D2B), high throughput experimentations (HTE), catalyst screening, electrochemistry, photo- redox, flow technology, and late-stage functionalization (LSF).
Our team of seasoned analytical scientists provides expert support in complex purification processes, final QC, and comprehensive structure elucidation for novel New Chemical Entities (NCEs). Our analytical and purification infrastructure includes advanced SFC capacity for chiral purification, ELSD/CAD techniques for purification and analysis of non-chromophoric compounds, and VCD analysis for accurate determination of absolute chirality.
We use proprietary and client-integrated electronic laboratory notebooks that are compliant with 21 CFR Part 11 requirements.
Our discovery chemistry platform is supported by experienced scientific talent, integrated project management practices and digital tools that help deliver chemistry solutions with speed, quality and consistency. As a full-service CRDMO, we offer flexible business models (FTE or FFS) and a customer-centric, no-conflict approach. This allows us to customize the size and composition of our teams, ensuring your project needs are met with faster cycle times. We ensure seamless transfer of compounds in assay plates or solids from our robotic compounds management to biology for running biological assays.
Aragen’s computational chemistry team brings deep expertise in informatics and AI/ML- driven approaches to accelerate drug design and development. Our capabilities span both structure-based and ligand-based drug design, supported by customized tools from Schrodinger and Cresset. By leveraging advanced data analytics platforms such as SARvision, DataWarrior, and other tailored solutions, we enhance the understanding of structure-activity relationships (SAR), enabling faster candidate identification and more efficient development cycles. Additionally, Aragen has developed its proprietary digital drug discovery platform, InCoRe, which ensures seamless data integration and workflow continuity across the Design-Make-Test-Analyze (DMTA) cycle.
Advancing Discovery Chemistry Through Digital Intelligence and AI Solutions
Aragen’s digital, AI-enabled and discovery chemistry capabilities support integrated workflows, data-driven insights and improved execution across discovery programmes.
Project-enabling tools like retrosynthetic tool, eProcurement, eSample, and eCuleNote (Aragen ELN) offer key metrics on operational excellence, driving the successful outcomes of discovery programs.
The core of our discovery process is the Collaboration Companion platform, which seamlessly unifies real-time data with AI-driven insights to monitor lab operations and delivery performance. This intelligent system enhances the entire preclinical discovery continuum by offering interactive dashboards and actionable performance metrics, enabling proactive decision-making and ensuring efficient, streamlined project execution.
Partner with Aragen to access integrated discovery chemistry capabilities supported by scientific expertise, digital tools and flexible engagement models.
2,500+ scientists and 300+ PhDs
India’s largest talent pool
XLRATE
proprietary project management platform to enable operational excellence
25+ Years of Scientific Leadership
in preclinical discovery
60,000+ Compounds
synthesized at different scale each year
Frequently Asked Questions (FAQs)
Aragen delivers integrated discovery chemistry including medicinal chemistry, synthetic chemistry, specialty chemistry, analytical support, peptide chemistry, and oligonucleotide synthesis.
Expert teams pair scientific know-how with AI/digital tools to design, synthesize, optimize, and characterize novel molecules for quicker candidate selection.
Aragen’s chemistry capabilities span small molecules, peptides, PROTACs, macrocycles, carbohydrates, nucleotides, ADCs and deuterated compounds.
All chemistry work follows rigorous documentation protocols with secure digital platforms that ensure data protection, IP confidentiality, and compliance with regulatory expectations.
Yes—Aragen's CRDMO model bridges hit ID/optimization, analytics, and scale-up for end-to-end workflows.
