Advancing drug discovery programs from idea to clinical candidate nomination.

Aragen biologists are well-positioned to meet the diverse drug discovery needs of our global life sciences customers. We work in a consultative manner to build relationships of trust. Our biology experts become an extension of customer internal R&D teams, guiding them through the discovery continuum, from study design and execution to interpretation of data and recommendations on the path forward.

Reagent generation scientists provide reagent proteins and engineered cell lines to support multiple screening campaigns by our assay development and screening team. Optimization of drug-like properties and bioavailability measurements are assisted by a broad panel of in vitro ADME assays and PK studies in rodents and other relevant species. Additionally, we provide in vivo proof-of-concept through our animal pharmacology models in several therapeutic areas. Our non-GLP exploratory toxicology and GLP in vitro toxicology studies provide early assessment of safety.

A customized project management platform enables scientists to focus on their science, while dedicated project management, logistics and supply chain teams ensure program efficiency, timely communication and rapid turnaround time.

Screening Assays

off-the-shelf and custom designed

Functional Proteins
& Engineered Cell Lines

supporting assay development and screening

Validated Animal
Models of Disease

in Oncology, Pain and Inflammation, Autoimmunity, Fibrosis, Cardiovascular and Metabolic Diseases