Aragen expertise in multiple methods of scaling-up antibody production, enables us to customize solutions for clients. We take a holistic approach to monoclonal antibody characterization, selecting analytical techniques and assays that best meet client needs, including biophysical and molecular techniques as well as efficacy measurements.
The production of monoclonal antibodies can be performed either by the scale-up of hybridomas or via cloning and expression using recombinant techniques. If a recombinant method is chosen, we may suggest isotype switching of the antibody or generate a human-mouse chimeric molecule should a human Fc domain be required for further efficacy evaluations. Our bioproduction capabilities run from from μg to gm scale.