Aragen offers fully integrated, end-to-end drug discovery and development services powered by advanced Digital & Artificial Intelligence (AI) solutions. Our expertise spans small molecules, biologics, and advanced modalities such as high-potency APIs (HPAPIs), antibody-drug conjugates (ADCs), peptides, oligonucleotides, and targeted degraders. With over 24 years of experience and 4,000+ scientists globally, we support your projects at every stage—from early discovery through development to successful commercialization.

Our expertise covers medicinal and synthetic chemistry, in vitro and in vivo biology (including efficacy models, DMPK, and cell & protein sciences), toxicology, and drug substance/product development under GMP and non-GMP standards.

Operating state-of-the-art facilities in the U.S. and India, we deliver high-quality results through scientific excellence, operational agility, and regulatory compliance, accelerating your drug discovery and development journey.

Aragen offers end-to-end solutions for small molecule solutions, from concept to commercial supply by combining deep expertise empowered by Digital and AI solutions:

• Chemistry: Medicinal chemistry, route scouting, process development, custom synthesis, and HPAPIs manufacturing, enhanced by AI-driven tools for real-time operational optimization.

• Biology: Advanced in vitro and in vivo pharmacology, DMPK, and cell & protein sciences for target validation and mechanistic insights, with automated assay workflows and data processing for faster, consistent, and high-quality results—boosting productivity.

• Toxicology: Comprehensive toxicology studies to de-risk your drug candidates.

• Drug Substance: We offer route scouting, process development, optimization, scale-up, and tech transfer services for small molecules, HPAPIs and ADCs using Quality by Design (QbD) principles and AI/ML to optimize critical process parameters from lab scale to commercial manufacturing, to deliver robust and reproducible processes.

• Drug Product: Our formulation development, analytical method development, and stability testing cover oral and parenteral dosage forms. Designed for full CMC compliance, these services accelerate your candidate’s path to market while ensuring quality and regulatory rigor.

• Manufacturing: We offer GMP and non-GMP manufacturing for drug substance and drug product across diverse modalities, with AI-driven process optimization—ensuring quality control, validated analytical methods, and stability programs that meet stringent regulatory standards—enhancing yield, efficiency, and consistency from early development through commercial supply.

Combining advanced project management with global GMP-capable facilities, we deliver seamless collaboration, rapid execution, and scalable manufacturing solutions that meet regulatory requirements throughout the entire product lifecycle.

Aragen Bioscience is a global CDMO specializing in biologics, with deep expertise in high-yield protein bioproduction and royalty-free cell line development. Our proprietary platforms have supported 100+ IND filings and multiple novel biological entities (NBEs).

We deliver Gene-to-GMP solutions in under 8 months, supporting:

• Antibodies (monoclonal antibodies, bispecific antibodies)

• Recombinant proteins

• Complex biologic modalities

From facilities in Morgan Hill, CA and Bengaluru, India, our flexible services include cell line development, process development (upstream and downstream), analytical characterization, and GMP manufacturing.

We provide advanced capabilities in complex therapeutic modalities:

• Antibody-Drug Conjugates (ADCs): Comprehensive synthesis, conjugation, and analytical support to develop potent targeted therapies.

• Peptides: Expertise in linear, branched, cyclic, stapled, and conjugated peptides using solid-phase, solution-phase, and hybrid synthesis methods. We synthesize small proteins (>150 amino acids) and offer non-GMP scale-up up to 500 grams. 

Targeted Degraders: Innovative development and synthesis of targeted protein degraders, leveraging cutting-edge chemistry and biology to enable next-generation therapeutic modalities.

• Over 24 years of industry experience supporting innovative drug discovery and development.

• A global network of 4,000+ scientists delivering scientific excellence and operational agility.

• State-of-the-art facilities across the U.S. and India ensuring quality, speed, and compliance.

• Proven track record with 100+ IND filings and multiple NBEs developed.

• Flexible engagement models—full-service or stage-specific support tailored to your needs.

• Integrated Digital & AI platforms driving operational excellence and faster timelines.

Discover how our end-to-end solutions for small and large molecules, powered by AI and Digital innovation, can transform your drug development process from concept to commercialization.

Visit us at BIO International or contact us to schedule a meeting.