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Brochure

PeptARx - Aragen’s Integrated Peptide Platform

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Who We Are

With 10+ years of peptide chemistry expertise, PeptARx supports innovators from concept to preclinical scale with end-to-end peptide services—delivered by 130 peptide chemists in Hyderabad. Our platform combines advanced synthetic chemistry,robust analytics, and scalable infrastructure to accelerate peptide discovery and development.

What We Deliver

One platform. Every peptide need

Custom Peptide Synthesis

Accelerate discovery with high quality custom peptides engineered for complexity, speed, and downstream development success.

  • Linear, branched, cyclic, stapled and bi-cyclic peptides
  • Challenging sequences; long peptides & protein fragments via NCL/KAHA
  • PNAs, peptoids, peptidomimetics
  • Peptide conjugation (fluorescent probe, lipid, PEG, protein, oligonucleotide, carbohydrate etc.)
  • Library & parallel synthesis with rapid crude to pure workflows
Unnatural Amino Acids (UAAs)

Expand chemical space with engineered building blocks tailored for potency, stability, and target selectivity.

  • 500+ catalogued UAAs across diverse chemical
    classes
  • 100+ custom UAA syntheses/year
  • Backbone engineering: N-alkylated, constrained,
    β-amino acids, glycosylated residues
  • Stereocontrol & functionalization: α/β selectivity, rigid scaffolds, bioorthogonal handles
  • Scalable integration: On resin insertion, solution incorporation, fragment coupling

Advanced Peptide Engineering

Unlock next-generation modalities with PeptARx through precision cyclization and structural constraint engineering for superior therapeutic performance.

Cyclization Technologies
Lactam bridges | Disulfide bonds | Click-based chemistry | Thioether formation | C–C stapling | Suzuki & Heck coupling

Using orthogonal protecting groups (Allyl, Alloc, Dde, Mtt, Pmb), we construct multi-bridged, highly constrained cyclic peptides with exceptional structural precision.

Peptide Conjugates

Enhance targeting, delivery, and imaging with PeptARx through multifunctional peptide conjugates designed for translational impact.

  • Peptide–drug / toxin conjugates
  • DOTA–metal scaffolds
  • GalNAc / Lipid / PEG conjugates
  • PPMO / POC / PDC
  • Peptide–protein bioconjugates
  • Fluorescent / tagged peptides (>1 g, >97% purity)
Scale Up & Non-GMP Supply
  • >500 g batches; purity >98%, scalable toward kilograms
  • Hybrid SPPS / solution phase strategies for difficult sequences
  • Reliable transition from discovery output to IND enabling volumes
Why PeptARx
  • Complex Chemistry Expertise: Long peptides, difficult sequences, multifunctional constructs
  • Advanced UAA Capability: Broad catalog, rapid custom design, stereocontrolled synthesis
  • Cutting-edge Engineering: Precision cyclization and conjugation for constrained architectures
  • High Throughput: 1,500+ linear and 2,500+ cyclic peptides/year
  • Quality Workflows: LCMS, HRMS, HPLC, 1H NMR with final QC and 24/7 purification
  • End-to-End Platform: Discovery to non-GMP scale-up under one roof