Industries we serve
- Pharma/ Biotech
- Medical Devices
- Plant Protection
- Industrial Chemicals
- Nutraceuticals
Test systems and routes of administration
Test Species
- Rats, mice, guinea pigs, rabbits, hamsters
- Dogs and Non-Human Primates, available through our
collaborating test facilities
Routes of Administration
- Oral (gavage & dietary), dermal, inhalation, parenteral (IV/SC/IM/ID)
- Other – Intranasal, ocular, intra-vitreal, otic, intra-articular;
- Implantation
Bioanalytical / Bioassay Solutions
- Single/Repeated Dose Pharmacokinetics
- Toxicokinetics
- Immunogenicity (ADA)
- Immunotoxicology
- Biomarkers
- Acute Phase Proteins
- Biodistribution/Persistence
Bioanalytical Techniques
- LC–MS (liquid chromatography–mass spectrometry)
- GC–MS (gas chromatography–mass spectrometry)
- HPLC (high performance liquid chromatography)
- Ligand binding assay (LBA) Platforms- ELISA and Meso Scale
Discovery (MSD)
Studies offered
Mutagenicity:
- In-vitro / in-vivo studies
- Gene mutation – Bacterial (Ames test); mammalian cells
- Chromosome Aberration; Micronucleus Test
Acute Toxicity:
- Acute oral, dermal, inhalation toxicity;
- Acute dermal & eye irritation/ corrosion; Mucous membrane irritation;
- Skin sensitization – Buehler, GPMT, LLNA
Subchronic / Chronic Toxicity / Carcinogenicity
- 7-day (DRF), 14-day, 28-day, 90-day, 180-day and
12-month repeat dose studies - 18-month/24-month carcinogenicity bioassays
- Implantation studies on medical devices
Reproductive Toxicity
- Fertility, Developmental toxicity, One/Multi-generation
studies
