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Brochure

Lipid Chemistry Capabilities

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Experience

  • Highly skilled team with over a decade of expertise in lipid chemistry.
  • Proficient in linear, cyclic, and complex phosphoramidite-linked lipids and PEG linkers.

Synthesis & Analytical Capabilities

  • Custom synthesis of scaffolds, expensive monomers, and final lipid compounds.
  • Scale flexibility: mg to multi-gram, with capability to scale up to Kg quantities.
  • Expertise in aminolipids, cholesterol, and phospholipids, covering molecular weight range 300–3500 Da.
  • Advanced characterization using 500 MHz NMR, GC-MS, and HRMS.
  • Cost optimization strategies for complex lipid projects.

Polymer Chemistry

  • Fully equipped to handle polymer chemistry, including larger molecules extended from lipids such as PEG-lipids.
  • Established a platform for large-molecule synthesis with molecular weights 1500+ Da.
  • Capability to design and synthesize functionalized polymers and lipid-polymer conjugates for advanced applications

Quality Control & Shipment

  • Deliverables with >95% purity confirmed by CAD analysis.
  • No residual CH2Cl2 or CHCl3; absence of CHCl3 verified via 1H NMR in CD3OD.
  • Comprehensive QC documentation provided with every shipment.
  • Cold-chain shipping through World Courier for global delivery.

Analysis & Purification

  • Method development and purity analysis using CAD coupled HPLC & SFC.
  • Quick screening and preparative scale-up with reverse-phase and achiral SFC stationary phases.
  • Mass-triggered purification for accurate fractionation and high-purity yields.
  • Purification from mg to multi-gram or Kg scale.
CAD
CAD detector
Preparative LC-MS System
Preparative LC-MS system

Why Aragen

  • Decade-plus experience in complex lipids.
  • Expertise in phosphoramidite and PEG linkers.
  • Proven ability to deliver high-purity lipids (>95%) at any scale.
  • Advanced analytical capabilities: HPLC/SFC, mass-triggered fractionation, 500 MHz NMR, GC-MS, HRMS.
  • Commitment to quality, scalability, and cold-chain logistics worldwide.

From milligrams to kilograms high-purity lipids delivered under cold-chain, worldwide.

Partner with us for precision, scalability, and reliability.